AX-024
AX-024 HCl is a small molecule cytokine release inhibitor that potently suppresses the production of pro-inflammatory cytokines including IL-6, TNF-α, IFN-γ, IL-10, and IL-17A. It is a valuable research tool for studying inflammatory and autoimmune diseases in both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
1704801-24-0
Product Name Alternative
Inhibit, Inhibitor, IFNAR, IFN-γ, Interferon-α/β receptor, Interferon-alpha/beta receptor, Interleukin, Interleukin Related, IL-10, IL Receptor, ILReceptor, IL-6, IL-17A, AX 024, AX 024 Hydrochloride, AX 024 hydrochloride, AX024, AX-024, AX-024 HCl, AX024 Hydrochloride, AX024 hydrochloride, AX-024 Hydrochloride, TNF Receptor, TNFR, TNF-α, Tumor Necrosis Factor Receptor
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
Inhibits TCR-dependent T cell activation
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml with warming) or in Water (up to 10 mg/ml with warming)
Smiles
Cl.COc1ccc2OCC (CN3CCCC3) =C (c3ccc (F) cc3) c2c1
Molecular Formula
C21H22FNO2·HCl
Molecular Weight
375.86
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[[4- (4-Fluorophenyl) -6-methoxy-2H-chromen-3-yl]methyl]pyrrolidine hydrochloride
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