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AX-024

AX-024 HCl is a small molecule cytokine release inhibitor that potently suppresses the production of pro-inflammatory cytokines including IL-6, TNF-α, IFN-γ, IL-10, and IL-17A. It is a valuable research tool for studying inflammatory and autoimmune diseases in both in vitro cellular assays and in vivo animal models.

Product Specifications

CAS Number

1704801-24-0

Product Name Alternative

Inhibit, Inhibitor, IFNAR, IFN-γ, Interferon-α/β receptor, Interferon-alpha/beta receptor, Interleukin, Interleukin Related, IL-10, IL Receptor, ILReceptor, IL-6, IL-17A, AX 024, AX 024 Hydrochloride, AX 024 hydrochloride, AX024, AX-024, AX-024 HCl, AX024 Hydrochloride, AX024 hydrochloride, AX-024 Hydrochloride, TNF Receptor, TNFR, TNF-α, Tumor Necrosis Factor Receptor

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

Inhibits TCR-dependent T cell activation

Form

Powder

Solubility

Soluble in DMSO (up to at least 25 mg/ml with warming) or in Water (up to 10 mg/ml with warming)

Smiles

Cl.COc1ccc2OCC (CN3CCCC3) =C (c3ccc (F) cc3) c2c1

Molecular Formula

C21H22FNO2·HCl

Molecular Weight

375.86

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

1-[[4- (4-Fluorophenyl) -6-methoxy-2H-chromen-3-yl]methyl]pyrrolidine hydrochloride

Available Sizes

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