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4-Hydroxytamoxifen

4-Hydroxytamoxifen is the primary active metabolite of the SERM Tamoxifen. It acts as a potent estrogen receptor antagonist with oral bioavailability and is widely used in breast cancer research, demonstrating antitumor efficacy in both in vitro cell culture and in vivo animal models.

Product Specifications

CAS Number

68047-06-3

Product Name Alternative

Progestogen Receptor, progestogenReceptor, trans-4-Hydroxytamoxifen, nucleus translocation, ICI 79280, ICI79280, ICI-79280, estrogen receptor, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, ER, ERR, 4-hydroxy Tamoxifen, 4Hydroxytamoxifen, 4-Hydroxytamoxifen, 4 Hydroxytamoxifen, (Z) -Afimoxifene, (Z) -4-hydroxy Tamoxifen

Field of Research

Metabolism Research

Purity

99.37% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.16 mM) ; H2O:< 0.1 mg/mL (insoluble) ; DMSO:58.3 mg/mL (150.45 mM)

Smiles

C (=C (/CC) \C1=CC=CC=C1) (\C2=CC=C (OCCN (C) C) C=C2) /C3=CC=C (O) C=C3

Molecular Formula

C26H29NO2

Molecular Weight

387.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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