4-Hydroxytamoxifen
4-Hydroxytamoxifen is the primary active metabolite of the SERM Tamoxifen. It acts as a potent estrogen receptor antagonist with oral bioavailability and is widely used in breast cancer research, demonstrating antitumor efficacy in both in vitro cell culture and in vivo animal models.
Product Specifications
CAS Number
68047-06-3
Product Name Alternative
Progestogen Receptor, progestogenReceptor, trans-4-Hydroxytamoxifen, nucleus translocation, ICI 79280, ICI79280, ICI-79280, estrogen receptor, Estrogen Receptor, Estrogen Receptor/ERR, EstrogenReceptor, ER, ERR, 4-hydroxy Tamoxifen, 4Hydroxytamoxifen, 4-Hydroxytamoxifen, 4 Hydroxytamoxifen, (Z) -Afimoxifene, (Z) -4-hydroxy Tamoxifen
Field of Research
Metabolism Research
Purity
99.37% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.16 mM) ; H2O:< 0.1 mg/mL (insoluble) ; DMSO:58.3 mg/mL (150.45 mM)
Smiles
C (=C (/CC) \C1=CC=CC=C1) (\C2=CC=C (OCCN (C) C) C=C2) /C3=CC=C (O) C=C3
Molecular Formula
C26H29NO2
Molecular Weight
387.51
Storage Conditions
-20°C
Notes
For research use only.
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