SLV-2436
SLV-2436 (SEL201-88) is a potent, ATP-competitive dual inhibitor of MNK1 and MNK2 kinases, exhibiting IC50 values of 10.8 nM and 5.4 nM, respectively. This compound is a valuable research tool for investigating MNK signaling in oncology, with utility in both in vitro biochemical assays and in vivo cancer models.
Product Specifications
CAS Number
2095704-43-9
Product Name Alternative
Mitogen activated protein kinase interacting kinase, MNK, MNK1, MNK2, MAPK interacting kinase, MAP kinase interacting kinase, SLV 2436, SLV2436, SLV-2436, SEL 201, SEL201, SEL-201, SEL201-88
Field of Research
Signal Transduction
Purity
98.56% (May vary between batches)
Solubility
DMSO:50 mg/mL (142.53 mM)
Smiles
Nc1n[nH]c2cc (ccc12) -c1ccc (=O) n (Cc2cccc (Cl) c2) c1
Molecular Formula
C19H15ClN4O
Molecular Weight
350.8
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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