CCT241736
CCT241736 is an orally active dual inhibitor of FLT3 and Aurora kinases, effective against resistant FLT3 mutants like ITD. This preclinical candidate shows potent activity in vitro and in vivo, supporting its development for acute myeloid leukemia (AML) in both adult and pediatric contexts.
Product Specifications
CAS Number
1402709-93-6
Product Name Alternative
Inhibit, Inhibitor, FLT3, Fms like tyrosine kinase 3, Aurora Kinase, AuroraKinase, CCT241736, CCT-241736, CCT 241736, Cluster of differentiation antigen 135, CD135
Field of Research
Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
96.20% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ;10% DMSO+90% Corn Oil:3.3 mg/mL (7.23 mM) ; DMSO:75 mg/mL (164.34 mM)
Smiles
Cc1nn (C) cc1-c1nc2c (N3CCN (Cc4ccc (Cl) cc4) CC3) c (Cl) cnc2[nH]1
Molecular Formula
C22H23Cl2N7
Molecular Weight
456.37
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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