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Olodanrigan

EMA401 is a potent and selective angiotensin II type 2 receptor (AT2R) antagonist. It inhibits AngII-induced p38/p42/p44 MAPK activation, reducing DRG neuron hyperexcitability, neurite outgrowth, and capsaicin sensitization in rodent and human models, making it a valuable research tool for neuropathic pain studies.

Product Specifications

CAS Number

1316755-16-4

Product Name Alternative

EMA401

Field of Research

Cardiovascular Research, Neuroscience

Purity

>98%

Form

Powder

Solubility

Soluble in DMSO (up to 35 mg/ml)

Smiles

COc1ccc2CN ([C@@H] (Cc2c1OCc1ccccc1) C (O) =O) C (=O) C (c1ccccc1) c1ccccc1

Molecular Formula

C32H29NO5

Molecular Weight

507.6

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S) -Benzyloxy-2-diphenylacetyl-6-methoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid

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