Tirapazamine
Tirapazamine (Win59075) is a hypoxia-activated cytotoxic prodrug that induces DNA single- and double-strand breaks, leading to apoptosis. It functions as a radiosensitizer and chemosensitizer, notably with cisplatin, and is applied in oncology research for studying hypoxia-targeted therapies in vitro and in vivo.
Product Specifications
CAS Number
27314-97-2
Product Name Alternative
Anticancer Agent, Bioreductive Agent, inhibit, Inhibitor, SML 0552, SML0552, SML-0552, SR 4233, SR 259075, SR4233, SR-4233, SR259075, SR-259075, Tirapazamine, Tirazone, Win 59075, Win59075, Win-59075
Field of Research
Cell Biology, Molecular Biology
Purity
96.65% (May vary between batches)
Solubility
DMSO:51 mg/mL (286.28 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.23 mM)
Smiles
On1c2ccccc2[n+] ([O-]) nc1=N
Molecular Formula
C7H6N4O2
Molecular Weight
178.15
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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