MK2-IN-1 hydrochloride
MK2-IN-1 hydrochloride is a potent and selective allosteric inhibitor of MAPKAPK2 (MK2), exhibiting an IC50 of 0.11 μM. This compound is a valuable research tool for studying p38 MAPK signaling in inflammatory processes and has been utilized in both cellular and animal models of inflammation and autoimmune diseases.
Product Specifications
CAS Number
1314118-94-9
Product Name Alternative
Inhibitor, MAP kinase activated protein kinase 2, MAPK activated protein kinase 2, MAPKAPK2 (MK2), MAPKAP kinase 2, inhibit, Mitogen-activated protein kinase activated protein kinase 2, MK 25, MK2, MK25, MK-25, MK2IN1 hydrochloride, MK-2-IN-1 hydrochloride, MK2-IN-1 Hydrochloride, MK2 IN 1 hydrochloride, MK2 Inhibitor
Field of Research
Metabolism Research, Signal Transduction
Purity
97.32% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.96 mM) ; DMSO:50 mg/mL (98.15 mM) ; H2O:Insoluble
Smiles
Cl.Clc1ccc (cc1) -c1ccc (o1) C (=O) N (Cc1ccccn1) c1ccc (cc1) N1CCNCC1
Molecular Formula
C27H26Cl2N4O2
Molecular Weight
509.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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