GIBH-130
GIBH-130 is a potent small molecule inhibitor of neuroinflammation, demonstrating high efficacy in suppressing IL-1β release from activated microglia with an IC50 of 3.4 nM. Its application is valuable for studying neuroinflammatory pathways in both cellular and animal models of neurological disorders.
Product Specifications
CAS Number
1252608-59-5
Product Name Alternative
Inhibitor, inhibit, IL-1β, ILReceptor, GIBH 130, GIBH130, GIBH-130, Interleukin Related, Interleukin, IL Receptor, TNF-α
Field of Research
Cell Biology, Immunology & Inflammation
Purity
99.52% (May vary between batches)
Solubility
H2O:Insoluble;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.55 mM) ; DMSO:27.5 mg/mL (76.3 mM)
Smiles
Cc1cc (nnc1C (=O) N1CCN (CC1) c1ncccn1) -c1ccccc1
Molecular Formula
C20H20N6O
Molecular Weight
360.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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