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Nemorubicin

Nemorubicin (PNU 152243) is a doxorubicin analog with a distinct antitumor spectrum, metabolic pathway, and toxicity. It demonstrates activity against tumors resistant to various chemotherapeutics, including alkylating agents and platinum drugs. Research applications include investigating its novel mechanism in both in vitro and in vivo models of multidrug-resistant cancers.

Product Specifications

CAS Number

108852-90-0

Product Name Alternative

PNU-152243A, PNU152243, PNU-152243, PNU 152243, Methoxymorpholinyl doxorubicin, Methoxymorpholinyldoxorubicin, Nemorubicin, inhibit, Inhibitor, FCE23762, FCE-23762, FCE 23762

Field of Research

Cell Biology, Molecular Biology

Purity

97.40% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (3.88 mM) ; DMSO:45 mg/mL (69.91 mM)

Smiles

[H][C@@]1 (C[C@@] (O) (Cc2c (O) c3C (=O) c4cccc (OC) c4C (=O) c3c (O) c12) C (=O) CO) O[C@H]1C[C@@H] ([C@H] (O) [C@H] (C) O1) N1CCO[C@@H] (C1) OC

Molecular Formula

C32H37NO13

Molecular Weight

643.64

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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