E7449
E7449 is a potent small molecule inhibitor of PARP1/2 and TNKS1/2, exhibiting low nanomolar IC50 values. It is a valuable research tool for studying DNA damage response and Wnt signaling pathways in both cellular and animal models of oncology and other diseases.
Product Specifications
CAS Number
1140964-99-3
Product Name Alternative
Inhibitor, PARP2, PARP, PARP1, poly ADP ribose polymerase, inhibit, E 7449, E7449, E-7449, Stenoparib, tankyrase1/2, UNII-9X5A2QIA7C
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
97.13% (May vary between batches)
Solubility
DMSO:6.4 mg/mL (20.17 mM)
Smiles
O=c1[nH][nH]c2nc (CN3Cc4ccccc4C3) nc3cccc1c23
Molecular Formula
C18H15N5O
Molecular Weight
317.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
129551-ML550 100 µL
MED8 (Mediator of RNA Polymerase II Transcription Subunit 8, Activator-recruited Cofactor 32kD Component, Mediator Complex Subunit 8, MGC17544, MGC19641) (MaxLight 550)
Sign In for Pricing
View Details 