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NMS-P118

NMS-P118 is a potent, selective, and orally bioavailable PARP-1 inhibitor. It is a valuable research tool for investigating PARP biology and has demonstrated antitumor activity in preclinical in vitro and in vivo models of cancer, particularly in BRCA-deficient contexts.

Product Specifications

CAS Number

1262417-51-5

Product Name Alternative

PARP, PARP1, PARP2, NMS-P 118, NMSP118, NMS-P118, NMS-P-118, NMS P118, inhibit, Inhibitor, poly ADP ribose polymerase

Field of Research

Epigenetics & Chromatin, Molecular Biology, Neuroscience

Purity

98.79% (May vary between batches)

Solubility

DMSO:16 mg/mL (40.46 mM)

Smiles

NC (=O) c1cc (F) cc2CN (C3CCN (CC3) C3CCC (F) (F) CC3) C (=O) c12

Molecular Formula

C20H24F3N3O2

Molecular Weight

395.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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