AS1517499
AS1517499 is a potent small molecule inhibitor of STAT6 phosphorylation with an IC50 of 21 nM. It is capable of crossing the blood-brain barrier, making it a valuable research tool for investigating STAT6-mediated pathways in both cellular assays and in vivo models of neuroinflammation and immune disorders.
Product Specifications
CAS Number
919486-40-1
Product Name Alternative
AS 1517499, AS1517499, AS-1517499, inhibit, Inhibitor, STAT, STAT6
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.27% (May vary between batches)
Solubility
DMSO:262.5 mg/mL (659.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.57 mM)
Smiles
NC (=O) c1cnc (NCCc2ccc (O) c (Cl) c2) nc1NCc1ccccc1
Molecular Formula
C20H20ClN5O2
Molecular Weight
397.86
Storage Conditions
-20°C
Notes
For research use only.
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