ICRT 14
ICRT 14 is a potent small-molecule inhibitor of β-catenin-dependent transcription, demonstrating an IC50 of 40.3 nM in Wnt pathway assays. It is a valuable research tool for studying Wnt/β-catenin signaling in cancer biology and stem cell research, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
677331-12-3
Product Name Alternative
Betacatenin, beta-catenin, bcatenin, Inhibitor, iCRT 14, iCRT14, iCRT-14, inhibit, Wnt/betacatenin, Wnt/b-catenin, Wnt, Wnt/β-catenin, βcatenin
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Purity
98.85% (May vary between batches)
Solubility
DMSO:12 mg/mL (31.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.33 mM)
Smiles
Cc1cc (C=C2SC (=O) N (C2=O) c2ccccc2) c (C) n1-c1cccnc1
Molecular Formula
C21H17N3O2S
Molecular Weight
375.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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