GSK-25
GSK-25 is a selective kinase inhibitor with IC50 values of 398 nM for RSK1 and 1000 nM for p70S6K, demonstrating good selectivity over a panel of 31 kinases and minimal cytochrome P450 inhibition (>2.2 μM) . It is a valuable research tool for studying RSK signaling pathways in cancer and metabolic disease models, both in vitro and in vivo.
Product Specifications
CAS Number
874119-56-9
Product Name Alternative
Inhibitor, GSK 25, GSK25, GSK-25, inhibit, mTOR (p70S6K), orally, p70S6K, blood, bioavailable, pressure, P450, selective, Ribosomal S6 Kinase (RSK), Rho-associated kinase, Rho-associated protein kinase, Rho-kinase, S6K, S6 Kinase, S6Kinase, ROCK, ROK, RSK1
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.59% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.9 mM) ; DMSO:60 mg/mL (116.88 mM)
Smiles
CC1=C (C (N=C (N1) c1ccnc (Cl) c1) c1ccc (Cl) cc1F) C (=O) Nc1cc2cn[nH]c2cc1F
Molecular Formula
C24H16Cl2F2N6O
Molecular Weight
513.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV811473 1.0 µg DNA
MGC24975 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details