Amifampridine
Amifampridine (3,4-Diaminopyridine) is a potassium channel blocker that prolongs neuronal action potentials, enhancing calcium influx and acetylcholine release at neuromuscular junctions. It is a key research tool for studying channelopathies and is applied in both in vitro electrophysiology and in vivo models of myasthenic syndromes.
Product Specifications
CAS Number
54-96-6
Product Name Alternative
Amifampridine, 3,4-Diaminopyridine, 3,4-Pyridinediamine, LEMS, Inhibitor, KcsA, inhibit, myasthenic syndrome, Oral, neurological disease, neuromuscular junction, Potassium Channel, PotassiumChannel, Pyridine-3,4-Diamine, voltage-gated potassium
Field of Research
Pharmacology & Drug Discovery
Purity
99.52% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (18.33 mM) ; H2O:24 mg/mL (219.92 mM) ; DMSO:60 mg/mL (549.8 mM)
Smiles
NC1=C (N) C=NC=C1
Molecular Formula
C5H7N3
Molecular Weight
109.13
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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