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Amifampridine

Amifampridine (3,4-Diaminopyridine) is a potassium channel blocker that prolongs neuronal action potentials, enhancing calcium influx and acetylcholine release at neuromuscular junctions. It is a key research tool for studying channelopathies and is applied in both in vitro electrophysiology and in vivo models of myasthenic syndromes.

Product Specifications

CAS Number

54-96-6

Product Name Alternative

Amifampridine, 3,4-Diaminopyridine, 3,4-Pyridinediamine, LEMS, Inhibitor, KcsA, inhibit, myasthenic syndrome, Oral, neurological disease, neuromuscular junction, Potassium Channel, PotassiumChannel, Pyridine-3,4-Diamine, voltage-gated potassium

Field of Research

Pharmacology & Drug Discovery

Purity

99.52% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (18.33 mM) ; H2O:24 mg/mL (219.92 mM) ; DMSO:60 mg/mL (549.8 mM)

Smiles

NC1=C (N) C=NC=C1

Molecular Formula

C5H7N3

Molecular Weight

109.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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