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Cucurbitacin IIA

Cucurbitacin IIA is a bioactive compound that induces apoptosis and enhances autophagy, contributing to its anti-inflammatory effects. It also acts as an anti-cancer agent by disrupting the actin cytoskeleton and inhibiting the JAK2/STAT3/survivin pathway, leading to PARP-mediated cell death. Its mechanisms are studied in vitro for oncology and inflammation-related disease research.

Product Specifications

CAS Number

58546-34-2

Product Name Alternative

Survivin, Inhibitor, inhibit, Hemslecin A, Curcurbitacin IIA, Cucurbitacin IIA, Dihydrocucurbitacin Q1, Apoptosis

Field of Research

Cell Biology

Purity

98.62% (May vary between batches)

Solubility

DMSO:91 mg/mL (161.71 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.55 mM) ; Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble

Smiles

[H][C@@]1 ([C@H] (O) C[C@@]2 (C) [C@]3 ([H]) CC=C4[C@@] ([H]) (C[C@H] (O) [C@@H] (O) C4 (C) C) [C@]3 (C) C (=O) C[C@]12C) [C@@] (C) (O) C (=O) CCC (C) (C) OC (C) =O

Molecular Formula

C32H50O8

Molecular Weight

562.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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