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MRE-269

MRE-269 (ACT-333679) is the long-acting, orally active metabolite of Selexipag and a potent prostacyclin receptor (IP receptor) agonist. It is utilized in pulmonary arterial hypertension (PAH) research, with studies demonstrating its efficacy in both in vitro assays and in vivo animal models of pulmonary hypertension.

Product Specifications

CAS Number

475085-57-5

Product Name Alternative

ACT 333679, ACT-333679, ACT333679, MRE 269, MRE269, MRE-269, inhibit, Inhibitor, ProstaglandinReceptor, prostaglandin I2 receptor, Prostaglandin Receptor

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Purity

98.25% (May vary between batches)

Solubility

DMSO:55 mg/mL (131.1 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (5.96 mM)

Smiles

N (CCCCOCC (O) =O) (C (C) C) C=1N=C (C (=NC1) C2=CC=CC=C2) C3=CC=CC=C3

Molecular Formula

C25H29N3O3

Molecular Weight

419.52

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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