β, β-Dimethylacrylshikonin
Dimethylacrylshikonin is a bioactive small molecule that demonstrates anti-tumor activity both in vitro and in vivo. It induces apoptosis in cancer cells like MCF-7 and SGC-791 by modulating Bcl-2/Bax, ERK, and NF-κB pathways, and enhances radiotherapy efficacy in HCT-116 xenograft models.
Product Specifications
CAS Number
24502-79-2
Product Name Alternative
Beta, beta-Dimethylacrylshikonin, beta, beta-Dimethylacrylshikonin, Dimethylacrylshikonin, b, b-Dimethylacrylshikonin, b, b-Dimethylacrylshikonin, inhibit, Isoarnebin I, HIFProlylHydroxylase, HIF/HIFProlylHydroxylase, HIF/HIF ProlylHydroxylase, HIF-1α, HIF Prolyl-Hydroxylase, HIF ProlylHydroxylase, HIF, Inhibitor, ERK, β, β-Dimethylacrylshikonin, β, β Dimethylacrylshikonin, β, βDimethylacrylshikonin, β, β-Dimethylacrylshikonin
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Neuroscience, Protein Biochemistry, Signal Transduction, Stem Cell & Developmental Biology
Purity
93.42% (May vary between batches)
Solubility
DMSO:8.55 mg/mL (23.08 mM)
Smiles
C\C (C) =C/C[C@@H] (OC (=O) \C=C (\C) C) C1=CC (=O) c2c (O) ccc (O) c2C1=O
Molecular Formula
C21H22O6
Molecular Weight
370.396
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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