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Thalidomide-5-NH2-CH2-COOH

Compound 114 (Thalidomide-5-NH2-CH2-COOH) is a bifunctional molecule acting as a selective protomyosin receptor kinase inhibitor and an E3 ligase ligand. It serves as a chemical probe for targeted protein degradation studies in oncology and neurological disease research, applicable in both cellular and animal models.

Product Specifications

CAS Number

2412056-27-8

Product Name Alternative

Inhibitor, E3 ligase, E3 ligase-recruiting Moiety, neurodegenerative, inhibit, inflammatory, infectious, Ligands for E3 Ligase, cancer, selective, tropomyosin receptor kinase, trk, Thalidomide5NH2CH2COOH, Thalidomide-5-NH-2-CH2-COOH, Thalidomide-5-NH2-CH2-COOH, Thalidomide 5 NH2 CH2 COOH, Thalidomide

Field of Research

Pharmacology & Drug Discovery

Purity

95.95% (May vary between batches)

Solubility

DMSO:3.32 mg/mL (10.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.02 mM)

Smiles

O=C1N (C (=O) C=2C1=CC (NCC (O) =O) =CC2) C3C (=O) NC (=O) CC3

Molecular Formula

C15H13N3O6

Molecular Weight

331.28

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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