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Thalidomide-O-C6-NH2 hydrochloride

This compound is a synthesized PROTAC linker-conjugate incorporating a thalidomide-based E3 ligase ligand. It is widely used in chemical biology and drug discovery research for constructing proteolysis-targeting chimeras (PROTACs) to study targeted protein degradation in vitro and in vivo.

Product Specifications

CAS Number

2245697-88-3

Product Name Alternative

DTAG-13, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, BET, 4- ((6-aminohexyl) oxy) -2- (2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione hydrochloride, FKBP12 (F36V), E3LigaseLigandLinkerConjugate, Inhibitor, inhibit, Thalidomide O C6 NH2 hydrochloride, ThalidomideOC6NH2 hydrochloride, Thalidomide-O-C-6-NH2 hydrochloride, Thalidomide-O-C6-NH2 Hydrochloride

Field of Research

Cell Biology, Pharmacology & Drug Discovery

Purity

97.45% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.05 mM) ; H2O:25 mg/mL (61 mM) ; DMSO:83.33 mg/mL (203.31 mM)

Smiles

O=C1N (C (CC2) C (NC2=O) =O) C (C3=C1C=CC=C3OCCCCCCN) =O.[H]Cl

Molecular Formula

C19H24ClN3O5

Molecular Weight

409.86

Storage Conditions

-20°C

Notes

For research use only.

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