Thalidomide-O-C6-NH2 hydrochloride
This compound is a synthesized PROTAC linker-conjugate incorporating a thalidomide-based E3 ligase ligand. It is widely used in chemical biology and drug discovery research for constructing proteolysis-targeting chimeras (PROTACs) to study targeted protein degradation in vitro and in vivo.
Product Specifications
CAS Number
2245697-88-3
Product Name Alternative
DTAG-13, E3 Ligase Ligand-Linker Conjugates, E3 Ligase LigandLinker Conjugate, E3 Ligase Ligand-Linker Conjugate, BET, 4- ((6-aminohexyl) oxy) -2- (2,6-dioxopiperidin-3-yl) isoindoline-1,3-dione hydrochloride, FKBP12 (F36V), E3LigaseLigandLinkerConjugate, Inhibitor, inhibit, Thalidomide O C6 NH2 hydrochloride, ThalidomideOC6NH2 hydrochloride, Thalidomide-O-C-6-NH2 hydrochloride, Thalidomide-O-C6-NH2 Hydrochloride
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
97.45% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.05 mM) ; H2O:25 mg/mL (61 mM) ; DMSO:83.33 mg/mL (203.31 mM)
Smiles
O=C1N (C (CC2) C (NC2=O) =O) C (C3=C1C=CC=C3OCCCCCCN) =O.[H]Cl
Molecular Formula
C19H24ClN3O5
Molecular Weight
409.86
Storage Conditions
-20°C
Notes
For research use only.
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