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Nur77 modulator 1

Nur77 modulator 1 is a small molecule binder of Nur77 (KD = 3.58 μM) that upregulates its expression and alters its subcellular localization. This induces Nur77-dependent ER stress, autophagy, and apoptosis, demonstrating anti-hepatoma activity in research models.

Product Specifications

CAS Number

2469975-55-9

Product Name Alternative

Antitumor, apoptosis, autophagy, Nur77 modulator 1, Nur-77 modulator 1, Nur77, mitochondria, inhibit, Inhibitor, good, stress, tolerability

Field of Research

Cell Biology, Immunology & Inflammation, Metabolism Research

Purity

98.11% (May vary between batches)

Solubility

DMSO:125 mg/mL (252.22 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (6.66 mM)

Smiles

COc1cccc2c (Nc3ccc4[nH]c (cc4c3) C (=O) N\N=C\c3ccc (SC) cc3) cc (C) nc12

Molecular Formula

C28H25N5O2S

Molecular Weight

495.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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