GNF2133
GNF2133 is a potent and selective DYRK1A inhibitor with an IC50 of 6.2 nM. It is a valuable research tool for studying type 1 diabetes, applicable in both in vitro enzymatic assays and in vivo models to investigate beta-cell proliferation and survival pathways.
Product Specifications
CAS Number
2561414-56-8
Product Name Alternative
Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, DYRK1A, DYRK, CD-1 mice, orally active, Inhibitor, inhibit, insulin secretion, GNF2133, GNF-2133, GNF 2133, glucose disposal, RIP-DTA mice, β-cell
Field of Research
Cell Biology, Signal Transduction
Purity
98.11% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (10.36 mM)
Smiles
CCN1CCN (CC1) C (=O) Nc1cc (ccn1) -c1cn (C2CCOCC2) c2cnccc12
Molecular Formula
C24H30N6O2
Molecular Weight
434.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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