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GNF2133

GNF2133 is a potent and selective DYRK1A inhibitor with an IC50 of 6.2 nM. It is a valuable research tool for studying type 1 diabetes, applicable in both in vitro enzymatic assays and in vivo models to investigate beta-cell proliferation and survival pathways.

Product Specifications

CAS Number

2561414-56-8

Product Name Alternative

Dual specificity tyrosine regulated kinase, Dual specificity tyrosine phosphorylation regulated kinase, DYRK1A, DYRK, CD-1 mice, orally active, Inhibitor, inhibit, insulin secretion, GNF2133, GNF-2133, GNF 2133, glucose disposal, RIP-DTA mice, β-cell

Field of Research

Cell Biology, Signal Transduction

Purity

98.11% (May vary between batches)

Solubility

DMSO:4.5 mg/mL (10.36 mM)

Smiles

CCN1CCN (CC1) C (=O) Nc1cc (ccn1) -c1cn (C2CCOCC2) c2cnccc12

Molecular Formula

C24H30N6O2

Molecular Weight

434.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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