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UNC3866

UNC3866 is a potent small molecule antagonist that disrupts the interaction between CBX7 and histone H3, as validated by AlphaScreen assays. This compound is a valuable chemical probe for studying Polycomb repressive complex 1 (PRC1) function in epigenetic regulation, cancer biology, and stem cell research in both cellular and biochemical experimental contexts.

Product Specifications

CAS Number

1872382-47-2

Product Name Alternative

CBX7-H3, inhibit, HistoneMethyltransferase, Histone Methyltransferase, Inhibitor, UNC3866, UNC-3866, UNC 3866

Field of Research

Epigenetics & Chromatin

Purity

88.06% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.52 mM) ; DMSO:79.5 mg/mL (100 mM)

Smiles

CCN (CC) CCCC[C@H] (NC (=O) [C@H] (CC (C) C) NC (=O) [C@H] (C) NC (=O) [C@H] (Cc1ccccc1) NC (=O) c1ccc (cc1) C (C) (C) C) C (=O) N[C@@H] (CO) C (=O) OC

Molecular Formula

C43H66N6O8

Molecular Weight

795.02

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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