MRTX-1719
MRTX-1719 is a highly potent and selective small molecule inhibitor of the PRMT5-MTA complex, demonstrating sub-10 nM IC50 activity in relevant cellular models. Its application facilitates research in oncology, particularly for investigating MTAP-deleted cancers in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
2630904-45-7
Product Name Alternative
CRC, Histone Methyltransferase, HistoneMethyltransferase, Inhibitor, inhibit, MRTX1719, MRTX-1719, MRTX 1719, MTA, NSCLC, PRMT5
Field of Research
Epigenetics & Chromatin
Purity
98.27% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.3 mM) ; DMSO:83.33 mg/mL (179.25 mM)
Smiles
CN1C (=C (C=N1) C=2C=C3C (=CC2) C (=O) NN=C3CN) C4=C (C#N) C (OC5CC5) =CC (Cl) =C4F
Molecular Formula
C23H18ClFN6O2
Molecular Weight
464.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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