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Phorbol

Phorbol (4β-Phorbol) is a diterpenoid natural product known for its potent tumor-promoting activity, which it exerts by directly activating Protein Kinase C (PKC) . It is extensively used as a research tool in both in vitro and in vivo studies to investigate PKC signaling pathways, cellular proliferation, and carcinogenesis mechanisms.

Product Specifications

CAS Number

17673-25-5

Product Name Alternative

(+) -Phorbol, 4β-Phorbol, 4b-Phorbol, 4beta-Phorbol, Phorbol, PKC

Field of Research

Epigenetics & Chromatin, Signal Transduction

Purity

98.20% (May vary between batches)

Solubility

DMSO:50 mg/mL (137.2 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.74 mM)

Smiles

C[C@@H]1[C@@H] (O) [C@]2 (O) [C@H] ([C@@H]3C=C (CO) C[C@@]4 (O) [C@@H] (C=C (C) C4=O) [C@@]13O) C2 (C) C

Molecular Formula

C20H28O6

Molecular Weight

364.43

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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