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L48H37

L48H37 is a chemically stable curcumin analog that acts as a specific myeloid differentiation protein 2 (MD2) inhibitor. It blocks LPS-TLR4/MD2 signaling and is applied in research models of sepsis and acute lung injury, both in vitro and in vivo.

Product Specifications

CAS Number

343307-76-6

Product Name Alternative

Asthma, Curcumin, lung injury, LPS-TLR4/MD2, Inflammation, IL-6, inhibit, L48H37, L-48H37, Inhibitor, TLR4/MD2, Sepsis, TNF-α, Toll-like Receptor (TLR)

Field of Research

Immunology & Inflammation

Purity

98.42% (May vary between batches)

Solubility

DMSO:45 mg/mL (93.06 mM)

Smiles

CCN1C\C (=C/c2cc (OC) c (OC) c (OC) c2) C (=O) \C (C1) =C\c1cc (OC) c (OC) c (OC) c1

Molecular Formula

C27H33NO7

Molecular Weight

483.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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