Monastrol
Monastrol is a cell-permeable small molecule that selectively inhibits the mitotic kinesin Eg5 (KIF11) . This action induces monopolar spindles and mitotic arrest, making it a valuable chemical tool for studying cell division mechanisms in both in vitro and in vivo cancer research models.
Product Specifications
CAS Number
329689-23-8
Product Name Alternative
Inhibit, Kinesin, Monastrol, Inhibitor, Eg5, Apoptosis, (±) -Monastrol
Field of Research
Cell Biology, Signal Transduction
Purity
98.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.84 mM) ; DMSO:55 mg/mL (188.13 mM)
Smiles
CCOC (=O) C1=C (C) NC (=S) NC1c1cccc (O) c1
Molecular Formula
C14H16N2O3S
Molecular Weight
292.35
Storage Conditions
-20°C
Notes
For research use only.
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