Thalidomide-5-methyl
Thalidomide-5-methyl is a cereblon (CRBN) ligand derived from thalidomide, used to recruit the CRBN protein in targeted protein degradation studies. This compound is a valuable tool for PROTAC development and investigating CRBN's role in both cellular and animal models of disease.
Product Specifications
CAS Number
40313-92-6
Product Name Alternative
E3 ligase-recruiting Moiety, inhibit, Ligands for E3 Ligase, LigandforE3Ligase, Ligand for E3 Ligase, Inhibitor, Thalidomide5methyl, Thalidomide-5-methyl, Thalidomide 5 methyl
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
99.48% (May vary between batches)
Solubility
DMSO:50 mg/mL (183.65 mM)
Smiles
O=C1N (C (=O) C=2C1=CC (C) =CC2) C3C (=O) NC (=O) CC3
Molecular Formula
C14H12N2O4
Molecular Weight
272.26
Storage Conditions
-20°C
Notes
For research use only.
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