Dantrolene sodium hemiheptahydrate
Dantrolene sodium is a hydantoin-derived muscle relaxant that inhibits skeletal muscle contraction by binding to the ryanodine receptor 1 (RyR1), thereby reducing calcium release from the sarcoplasmic reticulum. It is widely used in research applications, including in vitro studies of excitation-contraction coupling and in vivo models of malignant hyperthermia and muscle spasticity.
Product Specifications
CAS Number
24868-20-0
Product Name Alternative
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.52% (May vary between batches)
Solubility
DMSO:16.67 mg/mL (41.75 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.25 mM)
Smiles
O.O.O.O.O.O.O.[NaH].[NaH].[O-][N+] (=O) c1ccc (cc1) -c1ccc (C=NN2CC (=O) NC2=O) o1.[O-][N+] (=O) c1ccc (cc1) -c1ccc (C=NN2CC (=O) NC2=O) o1
Molecular Formula
C14H9N4NaO5·3.5H2O
Molecular Weight
399.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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