CAY10602
CAY10602 is a potent and selective SIRT1 activator identified via high-throughput screening. It dose-dependently inhibits NF-κB signaling and TNF-α production, as demonstrated in LPS-stimulated THP-1 cell assays with ~75% inhibition at 60 μM. This compound is a valuable research tool for studying SIRT1's role in inflammation, aging, and metabolic pathways in vitro.
Product Specifications
CAS Number
374922-43-7
Product Name Alternative
Inhibit, Inhibitor, CAY10602, CAY-10602, CAY 10602, Sirtuin, SIRT1
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
98.87% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.78 mM) ; DMSO:41.8 mg/mL (99.89 mM)
Smiles
Nc1c (c2nc3ccccc3nc2n1-c1ccc (F) cc1) S (=O) (=O) c1ccccc1
Molecular Formula
C22H15FN4O2S
Molecular Weight
418.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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