CVT-12012
CVT-12012 is a potent and orally bioavailable small molecule inhibitor of stearoyl-CoA desaturase (SCD), demonstrating an IC50 of 6.1 nM in HepG2 cells. This inhibitor is a valuable research tool for investigating lipid metabolism in models of metabolic disease, cancer, and non-alcoholic fatty liver disease (NAFLD) in both in vitro and in vivo studies.
Product Specifications
CAS Number
1018675-35-8
Product Name Alternative
CVT12012, CVT-12012, CVT 12012, inhibit, human HEPG2, Inhibitor, rat microsomal, Stearoyl-CoA Desaturase, StearoylCoADesaturase, StearoylCoA Desaturase (SCD), Stearoyl-CoA Desaturase (SCD), StearoylCoADesaturase (SCD), SCD
Field of Research
Metabolism Research
Purity
99.56% (May vary between batches)
Solubility
DMSO:125 mg/mL (287.75 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.21 mM)
Smiles
Cc1nc2ccc (NCc3cccc (c3) C (F) (F) F) cc2n (CCNC (=O) CO) c1=O
Molecular Formula
C21H21F3N4O3
Molecular Weight
434.41
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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