Buclizine dihydrochloride
Buclizine dihydrochloride is a histamine H1 receptor antagonist used in research for its antiemetic and antivertigo properties. It acts by blocking central muscarinic and histamine receptors, inhibiting the chemoreceptor trigger zone. This compound is applied in neuropharmacology studies investigating nausea, vomiting, and vestibular function in experimental models.
Product Specifications
CAS Number
129-74-8
Product Name Alternative
Cholinergic, anti-tumor activity, antihistamine, antiallergic, Buclina, Buclizine, Buclizine Dihydrochloride, Buclizine dihydrochloride, Buclizine HCl, 5HTReceptor, 5HT Receptor, Longifene, Inhibitor, inhibit, HT, HistamineReceptor, Histamine Receptor, MCF-7, UCB 4445, UCB4445, UCB-4445, teratogen
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
98.05% (May vary between batches)
Solubility
DMSO:11 mg/mL (21.74 mM)
Smiles
CC (C) (C) c1ccc (cc1) CN1CCN (CC1) C (c1ccccc1) c1ccc (cc1) Cl.Cl.Cl
Molecular Formula
C28H33ClN2·2HCl
Molecular Weight
505.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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