What is the catalog number for Butein?

The catalog number for Butein is orb1300778.

What sizes are available for Butein?

Butein is available in the following size(s): 1 mg, 2 mg, 5 mg, 1 ml x 10 mM (in DMSO), 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does Butein come in?

Butein is available in 8 different pack sizes.

Butein is currently made to order / not held in immediate stock. Contact us for lead time.

Butein

Butein is a multi-target small molecule that acts as a cAMP-specific PDE inhibitor, a protein tyrosine kinase inhibitor, and a SIRT1 activator. Research indicates it can sensitize HeLa cells to Cisplatin-induced cytotoxicity by modulating FoxO3a through the AKT and ERK/p38 MAPK signaling pathways, highlighting its utility in cancer research.

Product Specifications

CAS Number

487-52-5

Product Name Alternative

Cell, Apoptosis, Autophagy, Butein, AKT, 2',3,4,4'-tetrahydroxy Chalcone, EGFR, Epidermal growth factor receptor, ErbB-1, ERK, FoxO3a, HER1, HepG2, HeLa, MAPK, PDE4, p60c-src, inhibit, Inhibitor, Phosphodiesterase (PDE), phosphodiesterase, PKB, SIRT1, p38

Field of Research

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction

Purity

98.76% (May vary between batches)

Solubility

10% DMSO+90% Saline:2.5 mg/mL (9.18 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:51 mg/mL (187.33 mM) ; DMSO:237.5 mg/mL (872.36 mM)

Smiles

Oc1ccc (C (=O) \C=C\c2ccc (O) c (O) c2) c (O) c1

Molecular Formula

C15H12O5

Molecular Weight

272.25

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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