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CGS 21680 Hydrochloride

CGS 21680 HCl is a potent and highly selective adenosine A2A receptor agonist (IC50=22 nM), exhibiting 140-fold selectivity for A2A over A1 receptors. It is widely used in vitro and in vivo to study adenosine signaling, neuroprotection, inflammation, and cardiovascular models.

Product Specifications

CAS Number

124431-80-7

Product Name Alternative

Inhibitor, inhibit, CGS 21680, CGS 21680 HCl, CGS 21680 Hydrochloride, CGS21680, CGS-21680, CGS21680 Hydrochloride, CGS-21680 Hydrochloride, A2, Adenosine Receptor, AdenosineReceptor, P1 receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

96.74% (May vary between batches)

Solubility

DMSO:53.6 mg/mL (100 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.73 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cl.CCNC (=O) [C@H]1O[C@H] ([C@H] (O) [C@@H]1O) n1cnc2c (N) nc (NCCc3ccc (CCC (O) =O) cc3) nc12

Molecular Formula

C23H29N7O6·HCl

Molecular Weight

535.98

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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