Dovitinib lactate hydrate
Dovitinib lactate hydrate (TKI258) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor with high potency against class III (FLT3, c-Kit), class IV (FGFR1/3), and class V (VEGFR1-4) receptors. It has been used in preclinical research, including in vitro cell-based assays and in vivo xenograft models, to study angiogenesis and oncogenic signaling in various cancers.
Product Specifications
CAS Number
915769-50-5
Product Name Alternative
Dovitinib (TKI258) Lactate, Dovitinib Lactate, Dovitinib lactate hydrate, Dovitinib lactate Hydrate, Cluster of differentiation antigen 135, CHIR-258 lactate, CD135, CD117, cKit, c-Kit, inhibit, multi-targeted, kinase, Platelet-derived growth factor receptor, PDGFRα, PDGFRβ, PDGFR, Inhibitor, FLT3, Fibroblast growth factor receptor, Fms like tyrosine kinase 3, FGFR, FGFR1, FGFR3, SCFR, tyrosine, TKI 258, TKI258, TKI-258, TKI258 lactate, Vascular endothelial growth factor receptor, VEGFR2, VEGFR1, VEGFR, VEGFR3, VEGFR3/FLT4
Field of Research
Cardiovascular Research, Signal Transduction
Purity
99.17% (May vary between batches)
Solubility
H2O:61 mg/mL (126.42 mM) ; Ethanol:1 mg/mL (2.07 mM) ; DMSO:13.89 mg/mL (28.79 mM)
Smiles
O.CC (O) C (O) =O.CN1CCN (CC1) c1ccc2nc ([nH]c2c1) -c1c (N) c2c (F) cccc2[nH]c1=O
Molecular Formula
C24H27FN6O4
Molecular Weight
482.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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