What is the catalog number for Encorafenib?

The catalog number for Encorafenib is orb1300725.

What sizes are available for Encorafenib?

Encorafenib is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg.

How many pack sizes does Encorafenib come in?

Encorafenib is available in 5 different pack sizes.

Is Encorafenib in stock?

Encorafenib is currently made to order / not held in immediate stock. Contact us for lead time.

Encorafenib

Encorafenib (LGX818) is a potent and selective oral inhibitor of the BRAF V600E mutation, with an IC50 of 0.3 nM. It is widely used in preclinical oncology research, demonstrating significant antitumor activity in both in vitro cellular assays and in vivo models of melanoma and colorectal cancer.

Product Specifications

CAS Number

1269440-17-6

Product Name Alternative

Raf, Raf kinases, B-Raf (V600E), Inhibitor, LGX 818, LGX818, LGX-818, Encorafenib, inhibit

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

98.64% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:9.3 mg/mL (17.22 mM) ; DMSO:257 mg/mL (475.92 mM) ; Ethanol:93 mg/mL (172.22 mM)