Fludarabine Phosphate
Fludarabine Phosphate is a fluorinated antimetabolite derived from vidarabine. Upon intracellular conversion to its active triphosphate form, it inhibits DNA synthesis enzymes like DNA polymerase alpha, disrupting tumor cell proliferation. It is widely used in research, including in vitro and in vivo studies, for investigating hematological cancers and chemotherapy mechanisms.
Product Specifications
CAS Number
75607-67-9
Product Name Alternative
DNA polymerase α, DNA polymerase δ, DNA Synthesis, DNASynthesis, Analog, Apoptosis, Inhibitor, NSC118218, NSC-118218, NSC 118218, NSC 312887 Phosphate, inhibit, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, NSC312887 Phosphate, NSC-312887 Phosphate, F-ara-A (NSC 312887) Phosphate, F-ara-AMP, fludara Phosphate, Fludarabine, Fludarabine Phosphate, RNA Synthesis, RNASynthesis
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.48 mM) ; DMSO:35 mg/mL (95.84 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:2 mg/mL (5.48 mM)
Smiles
Nc1nc (F) nc2n (cnc12) [C@@H]1O[C@H] (COP (O) (O) =O) [C@@H] (O) [C@@H]1O
Molecular Formula
C10H13FN5O7P
Molecular Weight
365.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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