Fludarabine Phosphate

Fludarabine Phosphate is a fluorinated antimetabolite derived from vidarabine. Upon intracellular conversion to its active triphosphate form, it inhibits DNA synthesis enzymes like DNA polymerase alpha, disrupting tumor cell proliferation. It is widely used in research, including in vitro and in vivo studies, for investigating hematological cancers and chemotherapy mechanisms.

Product Specifications

CAS Number

75607-67-9

Product Name Alternative

DNA polymerase α, DNA polymerase δ, DNA Synthesis, DNASynthesis, Analog, Apoptosis, Inhibitor, NSC118218, NSC-118218, NSC 118218, NSC 312887 Phosphate, inhibit, Nucleoside Antimetabolite, Nucleoside Antimetabolite/Analog, NucleosideAntimetabolite, NSC312887 Phosphate, NSC-312887 Phosphate, F-ara-A (NSC 312887) Phosphate, F-ara-AMP, fludara Phosphate, Fludarabine, Fludarabine Phosphate, RNA Synthesis, RNASynthesis

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.48 mM) ; DMSO:35 mg/mL (95.84 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:2 mg/mL (5.48 mM)