GW-5074
GW 5074 is a potent and selective c-Raf inhibitor (IC50=9 nM) with demonstrated utility in studying MAPK/ERK signaling pathways in cellular and animal models of cancer and neurological diseases. It exhibits high specificity, showing no activity against a panel of other kinases including JNK, MEK, and VEGFR2.
Product Specifications
CAS Number
220904-83-6
Product Name Alternative
C-Raf, Apoptosis, inhibit, Inhibitor, GW5074, GW-5074, GW 5074, Raf, Raf kinases, Raf1 Kinase Inhibitor I
Field of Research
Neuroscience
Purity
>98%
Bioactivity
C-Raf1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) .
Smiles
C (=C1C=2C (NC1=O) =CC=C (I) C2) C3=CC (Br) =C (O) C (Br) =C3
Molecular Formula
C15H8Br2INO2
Molecular Weight
521.0
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3- (3,5-Dibromo-4-hydroxybenzylidene) -5-iodo-1,3-dihydroindol-2-one
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