Halobetasol propionate
Halobetasol propionate is a synthetic corticosteroid used in research for its potent anti-inflammatory and antipruritic effects. It acts by binding to glucocorticoid receptors, inhibiting arachidonic acid release and subsequent prostaglandin synthesis. This mechanism is studied in vitro and in vivo models of dermatological conditions like psoriasis and eczema to understand cutaneous inflammation and vascular responses.
Product Specifications
CAS Number
66852-54-8
Product Name Alternative
CGP 14458, CGP14458, CGP-14458, BMY 30056, BMY30056, BMY-30056, Halobetasol (propionate), Halobetasol Propionate, inhibit, Inhibitor, PLA2, Ulobetasol Propionate, Ulobetasol propionate
Field of Research
Metabolism Research
Purity
99.85% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.8 mM) ; DMSO:90 mg/mL (185.58 mM) ; Ethanol:36 mg/mL (74.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCC (=O) O[C@@]1 ([C@@H] (C) CC2C3C[C@H] (F) C4=CC (=O) C=CC4 (C) [C@@]3 (F) C (O) CC12C) C (=O) CCl
Molecular Formula
C25H31ClF2O5
Molecular Weight
484.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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