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Halobetasol propionate

Halobetasol propionate is a synthetic corticosteroid used in research for its potent anti-inflammatory and antipruritic effects. It acts by binding to glucocorticoid receptors, inhibiting arachidonic acid release and subsequent prostaglandin synthesis. This mechanism is studied in vitro and in vivo models of dermatological conditions like psoriasis and eczema to understand cutaneous inflammation and vascular responses.

Product Specifications

CAS Number

66852-54-8

Product Name Alternative

CGP 14458, CGP14458, CGP-14458, BMY 30056, BMY30056, BMY-30056, Halobetasol (propionate), Halobetasol Propionate, inhibit, Inhibitor, PLA2, Ulobetasol Propionate, Ulobetasol propionate

Field of Research

Metabolism Research

Purity

99.85% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.8 mM) ; DMSO:90 mg/mL (185.58 mM) ; Ethanol:36 mg/mL (74.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CCC (=O) O[C@@]1 ([C@@H] (C) CC2C3C[C@H] (F) C4=CC (=O) C=CC4 (C) [C@@]3 (F) C (O) CC12C) C (=O) CCl

Molecular Formula

C25H31ClF2O5

Molecular Weight

484.96

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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