Hesperadin
Hesperadin is a potent Aurora B inhibitor (IC50=250 nM) that also suppresses AMPK, MAPKAP-K1, Lck, CHK1, and PHK in vitro, though it does not inhibit MKK1 activity in vivo. This small molecule is a valuable research tool for studying cell division, kinase signaling pathways, and cancer biology in experimental models.
Product Specifications
CAS Number
422513-13-1
Product Name Alternative
Bloodstream, Autophagy, Aurora, AuroraKinase, Aurora Kinase, Aurora B (human), forms, Inhibitor, Hesperadin, inhibit, InfluenzaVirus, Influenza Virus, Parasite, TbAUK1, procyclic
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology
Purity
98.04% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.87 mM) ; DMSO:55.3 mg/mL (107.04 mM) ; Ethanol:27.7 mg/mL (53.61 mM)
Smiles
CCS (=O) (=O) Nc1ccc2NC (=O) \C (=C (/Nc3ccc (CN4CCCCC4) cc3) c3ccccc3) c2c1
Molecular Formula
C29H32N4O3S
Molecular Weight
516.65
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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