JZL-184
JZL 184 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor, exhibiting an IC50 of 8 nM for MAGL versus 4 μM for FAAH. This tool compound is widely used in neuroscience research to study endocannabinoid signaling in both in vitro assays and in vivo models.
Product Specifications
CAS Number
1101854-58-3
Product Name Alternative
MAGL, hydrolysis, Inhibitor, neurons, JZL 184, JZL184, JZL-184, Monoacylglycerol lipase, inhibit, analgesia, antinociceptive, 2-Arachidonoylglycerol
Field of Research
Neuroscience
Purity
>98%
Bioactivity
MAG lipase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
OC (C1CCN (CC1) C (=O) Oc1ccc (cc1) [N+] ([O-]) =O) (c1ccc2OCOc2c1) c1ccc2OCOc2c1
Molecular Formula
C27H24N2O9
Molecular Weight
520.50
Storage Conditions
RT
Notes
For research use only.
Other Product Names
4-Nitrophenyl-4- (dibenzo[d][1,3]dioxol-5-yl (hydroxyl) methyl) piperidine-1-carboxylate
Available Sizes
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