K-Ras (G12C) inhibitor 12
This small molecule is a selective, allosteric inhibitor of the oncogenic K-Ras (G12C) mutant protein. It is a valuable research tool for investigating Ras-driven cancers in both biochemical assays and cellular studies, supporting the development of targeted cancer therapies.
Product Specifications
CAS Number
1469337-95-8
Product Name Alternative
Apoptosis, K Ras (G12C) inhibitor 12, inhibit, K-Ras (G12C), KRas (G12C) inhibitor 12, K-Ras (G12C) inhibitor 12, K-Ras (G-12C) inhibitor 12, Inhibitor, Ras
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.16% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:26 mg/mL (57.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.22 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Oc1cc (Cl) c (I) cc1NCC (=O) N1CCN (CC1) C (=O) C=C
Molecular Formula
C15H17ClIN3O3
Molecular Weight
449.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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