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K-Ras (G12C) inhibitor 12

This small molecule is a selective, allosteric inhibitor of the oncogenic K-Ras (G12C) mutant protein. It is a valuable research tool for investigating Ras-driven cancers in both biochemical assays and cellular studies, supporting the development of targeted cancer therapies.

Product Specifications

CAS Number

1469337-95-8

Product Name Alternative

Apoptosis, K Ras (G12C) inhibitor 12, inhibit, K-Ras (G12C), KRas (G12C) inhibitor 12, K-Ras (G12C) inhibitor 12, K-Ras (G-12C) inhibitor 12, Inhibitor, Ras

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

97.16% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:26 mg/mL (57.82 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.22 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Oc1cc (Cl) c (I) cc1NCC (=O) N1CCN (CC1) C (=O) C=C

Molecular Formula

C15H17ClIN3O3

Molecular Weight

449.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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