KW-2478
KW-2478 is a potent small molecule inhibitor of HSP90 with an IC50 of 3.8 nM. It is a non-ansamycin compound used in cancer research to study oncogenic client protein degradation in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
819812-04-9
Product Name Alternative
Heat shock proteins, Inhibitor, HSP, HSP90, inhibit, KW 2478, KW2478, KW-2478
Field of Research
Metabolism Research, Signal Transduction
Purity
98.68% (May vary between batches)
Solubility
Ethanol:3 mg/mL (5.22 mM) ; DMSO:106 mg/mL (184.46 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.7 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CCc1c (O) cc (O) c (C (=O) c2ccc (OCCN3CCOCC3) c (OC) c2) c1CC (=O) N (CCOC) CCOC
Molecular Formula
C30H42N2O9
Molecular Weight
574.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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