ME-0328
ME0328 is a potent small molecule inhibitor exhibiting high selectivity for PARP3, with an IC50 of 0.89 μM and approximately 7-fold selectivity over PARP1. This compound is a valuable chemical probe for investigating PARP3-specific functions in DNA repair pathways, supporting both in vitro biochemical assays and cellular mechanism-of-action studies.
Product Specifications
CAS Number
1445251-22-8
Product Name Alternative
PARP, PARP3, PARP1, inhibit, Inhibitor, ME0328, ME-0328, ME 0328, poly ADP ribose polymerase
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
>98%
Bioactivity
PARP3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml), or in Ethanol (up to 4 mg/ml with warming) .
Smiles
C[C@H] (NC (=O) CCc1nc2ccccc2c (=O) [nH]1) c1ccccc1
Molecular Formula
C19H19N3O2
Molecular Weight
321.38
Storage Conditions
RT
Notes
For research use only.
Other Product Names
3,4-Dihydro-4-oxo-3,4-Dihydro-4-oxo-N-[ (1S) -1-phenylethyl]-2-quinazolinepropanamide
Available Sizes
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